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Restorative Retinal Lab

Research Interests

Our lab is dedicated to finding treatments for retinal and macular degenerative diseases. We generate patient-derived iPSC-RPE models and retinal organoids to decipher the underlying mechanisms of the disease and develop treatments. We are developing innovative gene therapy delivery systems, and use high throughput screening approaches for drug discovery.

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Selected Publications

Sher, I et al. "Novel suprachoroidal delivery system for injection of high volumes and rapid distribution of bevacizumab throughout the choroid layers." European Journal of Pharmaceutics and Biopharmaceutics. 2021

Sher, I et al. "Synthetic 9-cis-beta-carotene inhibits photoreceptor degeneration in cultures of eye cups from rpe65rd12 mouse model of retinoid cycle defect". Scientific Reports 2020

Sher, I et al. "Chromatic pupilloperimetry measures correlate with visual acuity and visual field defects in retinitis pigmentosa patients". Transl Vis Sci Technol. 2020

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